Hi,
It all depends upon your area and current soil nutrient status.
Papaya plant needs heavy doses of manures and fertilizers. Apart from the basal dose of manures (@ 10 kg./plant) applied in the pits, 200-250 g. each of N, P2O5 and K2O are recommended for getting high yield. Application of 200 g. N is optimum for fruit yield but papain yield increases with increase in N upto 300 g.
Micro-nutrients viz. ZnSO4 (0.5%) and H2 BO3 (0.1%) are sprayed in order to increase growth and yield characters.